Apollo was in love with Coronis, but Coronis was quite flirtatious. One day, Apollo had to go away, but he hesitated to leave Coronis alone, so he assigned crows to watch over her. Unfortunately, the crows failed in their mission, and as a result, Apollo cursed them. In this mythological tale, they were transformed from their white and beautiful appearance into a black and ill-voiced bird species. Apollo begged his twin sister Artemis to take revenge and requested her to kill Coronis. However, Coronis was carrying a baby in her womb. Later, the baby who would become the God of Medicine, Asclepius, was entrusted to Chiron, who would teach him everything about health, and Coronis' life ended.

The Rod of Asclepius, also known as the Staff of Aesculapius, snakes of which was given to Asklepios by Athena, and as the Asklepian, is a serpent-entwined rod wielded by the god Asclepius, a deity associated with healing and medicine. In modern times, it is the predominant symbol for treatment and health care, although it is sometimes confused with the similar caduceus, which has two snakes.

Asklepios' healing people through various methods anger Hades, as it prevents anyone from going to Tartarus. According to some accounts, Hades requested Zeus to kill Asklepios, and his request was fulfilled when Zeus struck him with lightning, causing his death and the garlic plant to occur from where he died. The proposal was not fulfilled in other versions, and Zeus transformed Asklepios into a constellation.

At the entrance of the Asklepion, where the snakes, which symbolize health because they are essentially reborn by shedding their skin, were used, tablets were found with the inscription "Death cannot enter." This guarantees that every patient accepted here will be cured.

Initially, members of the Asclepiad family were healed, but as the number of patients increased, unrelated individuals began to seek treatment, emphasizing the necessity of the "Hippocratic Oath."

Before employing various healing methods that also involved the use of snakes, patients would wear white garments symbolizing cleanliness and would be purified in sacred water. Offerings such as food, money, holy animals, or a diseased organ made of metal or baked clay were presented as sacrifices. Asklepios still accepted those who were unable to make any donations.

Methods of Healing:

1. Sleep: Treatment involved sleeping in a room called "Abaton" with snakes roaming around, and the dreams experienced during sleep were interpreted. Sometimes, interpretation was not required, as the plan brought healing. If a patient did not dream, they had to repeat the process the next day, known as the "Incubation Method."

2. Diet and Exercise: In cases where lack of motivation and physical activity were considered the cause of the illness, various diet and exercise programs were implemented. The exercises were more focused on mental health rather than intense physical activities. These included running in the sacred area, walking barefoot on the ground, various stretching movements, and horseback riding.

3. Water Therapy: Water consumption was considered sacred, and bathing was believed to have healing effects. Religious water sources rich in minerals were available. Mud baths or hot and cold therapeutic baths were administered.

4. Sunbathing: Like water, the sun was also believed to have healing effects. The sacred area included terraces constructed explicitly for this purpose, surrounded by walls. Massages with special oils and herbs were also provided to the patients in the exact location.

To assist patients in their recovery and maintain their morale, three annual festivals were held, including poetry and music competitions, athletic games, theatrical performances, and speeches dedicated to the gods. Small-scale sacrifices accompanied these festivals.

As a last resort, surgical interventions were also performed. Considering the risks, such as bleeding and infection during and after surgery, it can be understood that it was not a method applied unless necessary.

The geographical features of the region demonstrate why Asklepion was located there. Situated at the foot of Mount Madra, surrounded by small hills, the city was sheltered from various air currents and had clean air, which positively impacted the patients.

Archaeological excavations conducted at the sacred area of Asklepion have frequently uncovered medical tools such as probes, needles, knives, spatulas, forceps, and tweezers.